Diabetes is a Greek word.
The term diabetes was first used by Aretius in the second century. It is a Greek word meaning siphon. Aretius used such a term because in this disease water does not stay in the body and uses the man’s body like a channel. At the time, Aretias described symptoms of the disease as excessive urination, excessive thirst, loss of weight, etc.
In 400 years BC, Sushruta gave a scientific analysis of this disease in India.
The earliest mention of this disease is found in Aber Paparas. It is attributed to the time of the year 1500 BC (BC). About 400 years BC, Sushruta gave a scientific analysis of this disease in India. Due to the loss of sugar in urine, Sushruta named the disease as diabetes. Sushruta has also treated two forms of the disease.
Type One (occurring in children) and Type Two (occurring in adults) diabetes. Sushruta also said that this disease can be controlled by dietary control and physical exercise. Since the Sushruta Samhita was written many times during the time of Bangbhatt till 600 AD, many consider the time of the Sushruta Samhita to be of the fifth and sixth centuries .
In the 17th century, Thomas Willis of Europe described the disease fully and was awarded a fellowship. John Rawl associated the word melitus with diabetes in 1809 which means honey. In this way, this disease came to be called diabetes mellitus.
On 11 January 1922, Leonard Thompson was given Insulin for the first time.
In 1889, Minokoski and Mering removed the pancreas of a dog and proved that the pancreas gland is responsible for diabetes. However, they could not pursue this historical discovery. Paul Langerhans made it clear in 1893 that certain cells of the pancreas produced a hormone that reduced sugar. Later this hormone was called Insulin.
But the discovery of insulin was tied with the Banting and Best. They were students of McLeod and studied at the University of Toronto in Canada. They both injected the extract of the pancreas gland into a dog extracting the pancreas and were able to prove that it reduces blood sugar. This incident is of 1921. On 11 January 1922, Leonard Thompson, a 14-year-old diabetic patient, was given insulin for the first time. Following this historic breakthrough, the Eli Lilly company began commercial production of insulins in the United States.
Elliott P. Joslin used insulin on 293 patients for the first time in the world.
Elliott P. Joslin of America used insulin on 293 patients for the first time in the world and gained the reputation of being the most popular diabetes expert of the twentieth century. Gradually killing animals was stopped for production of Insulin, and was replaced by the DNA recombination technology, and the purest human insulin became available. Monocomponent insulins began to be available from 1970 onwards.
Since 1970, the market has rapidly filled with oral drugs . New medicines like Glibenclamide, Glipizide, etc. were quite safe and effective. In 1957, a very important drug called Metformin was discovered. Two very important research in the history of diabetes called DCCT Trial and UKPDS took place in 1993 and 1998 respectively which made fundamental changes in our beliefs.
The history of diabetes is exciting.
The history of diabetes is exciting. For centuries, it has been called a disease. Sushruta had pointed towards genetic influences in its occurrence. The DPP trial concluded that diabetes can be avoided by eating properly and exercising regularly. This information is the most important discovery after the discovery of insulin.